The Connection Between Obesity and Disease Epidemiology

ID-10011807An abundance of fat in the body has a number of negative effects, and some of them have been recently characterized by researchers. Being obese can lead to diabetes and number of other related disorders, and studies show how it allows pathogens in the body to survive.

Take hepatitis, for example. Hepatitis C disease is caused by a virus that infiltrates and leads to a chronic infection based upon the viral load. The population that’s affected by HCV is on the rise, and there are a number of cases where individuals have been diagnosed with fatty liver. This may result in liver steasosis and can also lead to extensive damage of the liver.

The fattening of the liver has been a focal point of research. show that obese people are more prone of viral infections because of the high fat content in their bodies. If there are a large number of fat bodies (liposomes) in the body, they serve as sites of entry for the virus. The virus can hide inside the liposome and easily enter the liver, later on causing damage.

Similar approach of research has been applied in the case of diabetes based treatment as well. In the case of diabetes, there are two cases. In one case, the immune cells of the body destroy the insulin producing cells. This is directly linked with obesity.

People already suffering from diabetes are recommended to modify their diets and also keep blood sugar levels in check to avoid weight gain when taking insulin. A number of monitoring devices are available that can help patients keep track of their levels.  for more details on the nature of continuous glucose monitoring and how it differs from other monitoring apps.

The liposomes that have been discussed earlier play an autoimmune role in the body. The immune cells of the body take fat cells as antigens and start an immune reaction. This can lead to the destruction of the cells, leading to diabetes.

One of the fundamental associations of obesity is with metabolic pathways. In the different metabolic pathways of your body, energy is generated and different essential molecules are synthesized. In the case of obesity, the metabolic pathways are modified since there’s a lot of fat coming in.

So what happens is that the metabolic pathways are adjusted at the expense of other important components which had to be synthesized. This can lead to harmful effects and is especially linked with clot development in cardiac muscles. This warrants using smart ways of keeping your weight in check.

It has become a focus area of research where the metabolic pathways of normal and diseased people are compared to see which components leave effects. The technical name for this study is fluxomics.

Through such researches, scientists have concluded how nearly all diseases have a certain metabolic component associated with them. There’s hope that by identifying the target, specific drugs can be made.

The excess fat that you store inside your body can allow different disease states to prevail inside. The more troublesome is the aspect of how pathogens can use fat components to enter inside the cells and propagate damage. This demands a higher focus on good nutrition and a well thought out exercise regimen.

Image courtesy of Michelle Meiklejohn /


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